Analysis of five deep-sequenced trio-genomes of the Peninsular Malaysia Orang Asli and North Borneo populations

Analysis of five deep-sequenced trio-genomes of the Peninsular Malaysia Orang Asli and North Borneo populations

Background: Recent advances in genomic technologies have facilitated genome-wide investigation of human genetic variations. However, most efforts have focused on the major populations, yet trio genomes of indigenous populations from Southeast Asia have been under-investigated. Results: We analyzed t...

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Bibliographic Details
Main Authors: Deng, L. (Author), Farhang, A. (Author), Hoh, B.-P (Author), Hoque, M.Z (Author), Jong, B. (Author), Kumar, S.V (Author), Liu, C. (Author), Lou, H. (Author), Lu, D. (Author), Marshall, C.R (Author), Ong, R.T.-H (Author), Phipps, M.E (Author), Scherer, S.W (Author), Teo, Y.-Y (Author), Thiruvahindrapuram, B. (Author), Thuhairah, A.R (Author), Wong, L.-P (Author), Xie, B. (Author), Xu, S. (Author), Xu, W. (Author), Yew, C.-W (Author), Zhang, X. (Author)
Format: Article
Language:English
Published: BioMed Central 2019
Subjects:
adult
AMY1A gene
animal
Animals
Article
autosome
Borneo
controlled study
copy number variation
DEFA1B gene
demography
DNA Copy Number Variations
ethnology
gene
gene duplication
gene mutation
genetic variability
genetic variation
Genetic Variation
genetics
genome analysis
Genome, Human
genomics
haplotype
high throughput sequencing
High-Throughput Nucleotide Sequencing
hominid
Hominidae
host resistance
human
human genome
Humans
indel mutation
INDEL Mutation
Malaysia
mutation rate
Mutation Rate
Orang Asli
pedigree
single nucleotide polymorphism
tropical rain forest
whole genome sequencing
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