ProPIP: a tool for progressive multiple sequence alignment with Poisson Indel Process

ProPIP: a tool for progressive multiple sequence alignment with Poisson Indel Process

Background: Current alignment tools typically lack an explicit model of indel evolution, leading to artificially short inferred alignments (i.e., over-alignment) due to inconsistencies between the indel history and the phylogeny relating the input sequences. Results: We present a new progressive mul...

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Bibliographic Details
Main Authors: Anisimova, M. (Author), Frei, D. (Author), Gatti, L. (Author), Gil, M. (Author), Leidi, T. (Author), Maiolo, M. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
algorithm
Algorithms
Alignment
Alignment software
article
Biology
C++ (programming language)
Computer operating systems
Dynamic programming
Evolution, Molecular
Evolutionary alignment
Indel evolution
indel mutation
INDEL Mutation
Insertions and deletions
licence
molecular evolution
Multiple sequence alignments
Multiple sequence alignmnet
Multiple sequences
Open source software
phylogeny
Phylogeny
Poisson indel process
Poisson Indel Process
punishment
sequence alignment
Sequence Alignment
Sequence alignmnet
software
Software
Source codes
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