SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency

SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency

Background: Introns are generally removed from primary transcripts to form mature RNA molecules in a post-transcriptional process called splicing. An efficient splicing of primary transcripts is an essential step in gene expression and its misregulation is related to numerous human diseases. Thus, t...

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Bibliographic Details
Main Authors: de Melo Costa, V.R (Author), Louloupi, A. (Author), Ørom, U.A.V (Author), Pfeuffer, J. (Author), Piro, R.M (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Aberrant transcript
alternative RNA splicing
Alternative Splicing
Cancer progression
Co-transcriptional splicing
Diseases
Dynamics
Efficiency
Gene expression
Gene expression levels
genetics
genome
Genome
High level languages
human
Humans
intron
Introns
ITS applications
Post-transcriptional process
Prostate cancers
RNA
RNA molecules
RNA splice site
RNA Splice Sites
RNA splicing
RNA Splicing
RNA-seq
Splicing dynamics
Splicing efficiency
User friendly
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