Proteome-wide analysis of Coxiella burnetii for conserved T-cell epitopes with presentation across multiple host species

Proteome-wide analysis of Coxiella burnetii for conserved T-cell epitopes with presentation across multiple host species

Background: Coxiella burnetii is the Gram-negative bacterium responsible for Q fever in humans and coxiellosis in domesticated agricultural animals. Previous vaccination efforts with whole cell inactivated bacteria or surface isolated proteins confer protection but can produce a reactogenic immune r...

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Bibliographic Details
Main Authors:	Durfee, C.J (Author), Piel, L.M.W (Author), White, S.N (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2021
Subjects:	Agricultural robots animal Animals Antigens, Bacterial Bacteria bacterial antigen bacterial vaccine Bacterial Vaccines bovine Cattle Coxiella burnetii Cross-species Cytology epitope Epitopes Epitopes, T-Lymphocyte Gram-negative bacteria Immune response Major histocompatibility complex Mammals Mice Model organisms mouse Peptide epitopes Peptides proteome Proteome Proteome-wide Proteome-wide analysis T-cell epitope T-cell epitopes T-cells Vaccine targets Vaccines
Online Access:	View Fulltext in Publisher

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