Proteome-wide analysis of Coxiella burnetii for conserved T-cell epitopes with presentation across multiple host species

Proteome-wide analysis of Coxiella burnetii for conserved T-cell epitopes with presentation across multiple host species

Background: Coxiella burnetii is the Gram-negative bacterium responsible for Q fever in humans and coxiellosis in domesticated agricultural animals. Previous vaccination efforts with whole cell inactivated bacteria or surface isolated proteins confer protection but can produce a reactogenic immune r...

Full description

Bibliographic Details
Main Authors: Durfee, C.J (Author), Piel, L.M.W (Author), White, S.N (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Agricultural robots
animal
Animals
Antigens, Bacterial
Bacteria
bacterial antigen
bacterial vaccine
Bacterial Vaccines
bovine
Cattle
Coxiella burnetii
Cross-species
Cytology
epitope
Epitopes
Epitopes, T-Lymphocyte
Gram-negative bacteria
Immune response
Major histocompatibility complex
Mammals
Mice
Model organisms
mouse
Peptide epitopes
Peptides
proteome
Proteome
Proteome-wide
Proteome-wide analysis
T-cell epitope
T-cell epitopes
T-cells
Vaccine targets
Vaccines
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items