Cytotoxic compounds from the stem bark of calophyllum soulattri

Cytotoxic compounds from the stem bark of calophyllum soulattri

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Chemical investigation of the stem bark of Calophyllum soulattri resulted in the isolation of a new phloroglucinol, namely calosubellinone (1) along with two known compounds, garsubellin B (2) and soulattrone A (3). The structures of these compounds were established on the basis of spectroscopic met...

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Bibliographic Details
Main Authors: Hemaroopini, S. (Author), Jong, V.Y.-M (Author), Lim, C.-K (Author), Say, Y.-H (Author)
Format: Article
Language:English
Published: Natural Product Incorporation 2017
Subjects:
antiproliferative activity
Article
bark
Calophyllum
Calophyllum soulattri
calosubellinone
Calosubellinone
cancer inhibition
cisplatin
controlled study
cytotoxic agent
Cytotoxicity
doxorubicin
drug cytotoxicity
drug isolation
drug screening
drug structure
embryo
garsubellin B
Garsubellin B
HeLa
HeLa cell line
human
human cell
IC50
LS174T
MDA-MB-231
MDA-MB-231 cell line
phloroglucinol
soulattrone A
T98G
unclassified drug
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