Women’s Pregnancy Life History and Alzheimer’s Risk: Can Immunoregulation Explain the Link?

Women’s Pregnancy Life History and Alzheimer’s Risk: Can Immunoregulation Explain the Link?

Background: Pregnancy is associated with improvement in immunoregulation that persists into the geriatric phase. Impaired immunoregulation is implicated in Alzheimer’s disease (AD) pathogenesis. Hence, we investigate the relationship between pregnancy and AD. Methods: Cross-sectional cohort of Briti...

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Bibliographic Details
Main Authors: Berzuini, C. (Author), Fox, M. (Author), Glynn, L.M (Author), Knapp, L.A (Author)
Format: Article
Language:English
Published: SAGE Publications Inc. 2018
Subjects:
adaptive immunity
adult
aged
Aged
Aged, 80 and over
Alzheimer disease
Alzheimer Disease
Alzheimer’s disease
Article
autoimmunity
Autoimmunity
Clinical Dementia Rating
cognitive defect
cohort analysis
controlled study
Cross-Sectional Studies
cross-sectional study
dementia
disease exacerbation
female
Female
first trimester pregnancy
human
Humans
immune system
immunoregulation
live birth
major clinical study
parity
Parity
physiology
pregnancy
Pregnancy
Pregnancy Trimester, First
reproductive history
risk assessment
risk factor
Risk Factors
semi structured interview
social status
stillbirth
third trimester pregnancy
time factor
Time Factors
United Kingdom
very elderly
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