Hepatoprotective activity of methanolic extract of bauhinia purpurea leaves against paracetamol-induced hepatic damage in rats

Hepatoprotective activity of methanolic extract of bauhinia purpurea leaves against paracetamol-induced hepatic damage in rats

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In an attempt to further establish the pharmacological properties of Bauhinia purpurea (Fabaceae), hepatoprotective potential of methanol extract of B. purpurea leaves (MEBP) was investigated using the paracetamol- (PCM-) induced liver toxicity in rats. Five groups of rats (n = 6) were used and admi...

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Bibliographic Details
Main Authors: Jakius, K.F (Author), Kamarolzaman, M.F.F (Author), Mahmood, N.D (Author), Mamat, S.S (Author), Mohtarrudin, N. (Author), Salleh, M.Z (Author), Seyedan, A.A (Author), Shahril, M.S (Author), Somchit, M.N (Author), Suhaili, Z. (Author), Susanti, D. (Author), Teh, L.K (Author), Yahya, F. (Author), Zakaria, Z.A (Author)
Format: Article
Language:English
Subjects:
1,1 diphenyl 2 picrylhydrazyl
alanine aminotransferase
alanine aminotransferase blood level
animal experiment
animal model
animal tissue
antioxidant activity
article
aspartate aminotransferase
aspartate aminotransferase blood level
Bauhinia purpurea extract
blood sampling
body weight
chemical analysis
controlled study
histopathology
in vitro study
in vivo study
liver injury
liver necrosis
liver protection
liver structure
liver toxicity
liver weight
lymphocytic infiltration
methanol
microscopy
nonhuman
paracetamol
plant leaf
priority journal
rat
scavenging system
silymarin
treatment duration
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