Genomic Stability and Genetic Defense Systems in Dolosigranulum pigrum, a Candidate Beneficial Bacterium from the Human Microbiome

Genomic Stability and Genetic Defense Systems in Dolosigranulum pigrum, a Candidate Beneficial Bacterium from the Human Microbiome

Dolosigranulum pigrum is positively associated with indicators of health in multiple epidemiological studies of human nasal microbiota. Knowledge of the basic biology of D. pigrum is a prerequisite for evaluating its potential for future therapeutic use; however, such data are very limited. To gain...

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Bibliographic Details
Main Authors: Bomar, L. (Author), Brugger, S.D (Author), Cotton, S.L (Author), Escapa, I.F (Author), Eslami, S.M (Author), Gao, W. (Author), Johnston, C.D (Author), Jones, D.S (Author), Lemon, K.P (Author), Minot, S. (Author), Ramos, S.F (Author), Roberts, R.J (Author), Skeete, C.A (Author), Tran, T.H (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
Subjects:
Article
bacterial strain
bacterium
child
chromosome
chromosome structure
comparative study
CRISPR Cas system
defense mechanism
Dolosigranulum pigrum
gene cluster
gene insertion sequence
genomic instability
genomics
horizontal gene transfer
host resistance
human
intestine flora
microbiome
mobile genetic element
molecular phylogeny
nonhuman
phylogenomics
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