Streptococcus pyogenes forms serotype- And local environment-dependent interspecies protein complexes

Streptococcus pyogenes forms serotype- And local environment-dependent interspecies protein complexes

Streptococcus pyogenes is known to cause both mucosal and systemic infections in humans. In this study, we used a combination of quantitative and structural mass spectrometry techniques to determine the composition and structure of the interaction network formed between human plasma proteins and the...

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Bibliographic Details
Main Authors: Bergdahl, G.E (Author), Chowdhury, S. (Author), Ekstrom, S. (Author), Happonen, L. (Author), Khakzad, H. (Author), Linke, D. (Author), Lood, R. (Author), Malmström, J. (Author), Malmström, L. (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
Subjects:
albumin
alpha 1 antitrypsin
Article
bacterium culture
binding site
comparative study
complement component C4b binding protein
computer model
controlled study
DIA-MS
host pathogen interaction
Host-pathogen interactions
immune evasion
immunoglobulin A
immunosurveillance
impetigo
liquid chromatography-mass spectrometry
M protein
M proteins
mass spectrometry
mucosa
necrotizing fasciitis
network analysis
nonhuman
open reading frame
plasma protein
protein expression
protein protein interaction
protein purification
protein structure
Protein-protein interactions
quantitative analysis
saliva protein
secretory component
secretory immunoglobulin
serotype
species difference
Streptococcus pyogenes
surface plasmon resonance
tonsillitis
virulence factor
X ray crystallography
XL-MS
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