Augmented Clearance of Nivolumab Is Associated with Renal Functions in Chronic Renal Disease Model Rats

The clinically approved dose of nivolumab is 240 mg every 2 weeks. However, previous studies have shown that baseline nivolumab clearance (CL) is associated with treatment outcomes in patients with solid cancers, thus motivating researchers to identify prognostic factors and indices influencing nivo...

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Bibliographic Details
Main Authors: Enoki, Y. (Author), Hamada, A. (Author), Hayashi, Y. (Author), Matsumoto, K. (Author), Ohuchi, M. (Author), Taguchi, K. (Author), Yagishita, S. (Author), Yamada, H. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
rat
Online Access:View Fulltext in Publisher