Serum Levels of Proinflammatory Lipid Mediators and Specialized Proresolving Molecules Are Increased in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 and Correlate With Markers of the Adaptive Immune Response

Serum Levels of Proinflammatory Lipid Mediators and Specialized Proresolving Molecules Are Increased in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 and Correlate With Markers of the Adaptive Immune Response

BACKGROUND: Specialized proresolution molecules (SPMs) halt the transition to chronic pathogenic inflammation. We aimed to quantify serum levels of pro- and anti-inflammatory bioactive lipids in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients, and to identify potential relation...

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Bibliographic Details
Main Authors: Barrett, D.A (Author), Chapman, V. (Author), Gohir, S.A (Author), Irving, W.L (Author), Jha, R.R (Author), Kim, D.-H (Author), Lunt, E. (Author), Ortori, C.A (Author), Tarr, A.W (Author), Tighe, P.J (Author), Turnbull, J. (Author), Valdes, A.M (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
adaptive immunity
Adaptive Immunity
Antibodies, Viral
anti-nucleocapsid
bioactive lipids
coronavirus spike glycoprotein
COVID-19
Eicosanoids
female
Female
human
Humans
icosanoid
immune response
male
Male
SARS-CoV-2
specialized proresolving molecules
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2
virus antibody
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