Effect of Mobile Phase pH on the Electrospray Ionization Efficiency and Qualitative Analysis of Pharmaceuticals in ESI + LC-MS/MS

Effect of Mobile Phase pH on the Electrospray Ionization Efficiency and Qualitative Analysis of Pharmaceuticals in ESI + LC-MS/MS

The effect of mobile phase pH on positive ionization process and retention time of nine pharmaceuticals on ultra-performance liquid chromatography-electrospray-tandem mass spectrometry (LC-MS/MS) was discussed. The effective use of high and low mobile phase pH in LC-MS/MS qualitative analyses method...

Full description

Bibliographic Details
Main Authors: Bakar, N.K.A (Author), Kafeenah, H.I.S (Author), Osman, R. (Author)
Format: Article
Language:English
Published: Oxford University Press 2019
Subjects:
chemical model
chemistry
Chromatography, Liquid
electrospray mass spectrometry
Hydrogen-Ion Concentration
ion
Ions
limit of detection
Limit of Detection
Linear Models
liquid chromatography
metformin
Metformin
Models, Chemical
pH
procedures
reproducibility
Reproducibility of Results
simvastatin
Simvastatin
Spectrometry, Mass, Electrospray Ionization
statistical model
tandem mass spectrometry
Tandem Mass Spectrometry
Online Access:View Fulltext in Publisher
View in Scopus

Internet

View Fulltext in Publisher
View in Scopus

Similar Items