Bridging the gaps in statistical models of protein alignment

SUMMARY: Sequences of proteins evolve by accumulating substitutions together with insertions and deletions (indels) of amino acids. However, it remains a common practice to disconnect substitutions and indels, and infer approximate models for each of them separately, to quantify sequence relationshi...

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Bibliographic Details
Main Authors: Allison, L. (Author), Konagurthu, A.S (Author), Sumanaweera, D. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Online Access:View Fulltext in Publisher