PolarMorphism enables discovery of shared genetic variants across multiple traits from GWAS summary statistics

MOTIVATION: Pleiotropic SNPs are associated with multiple traits. Such SNPs can help pinpoint biological processes with an effect on multiple traits or point to a shared etiology between traits. We present PolarMorphism, a new method for the identification of pleiotropic SNPs from genome-wide associ...

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Bibliographic Details
Main Authors: de Ridder, J. (Author), Ten Dam, M. (Author), van der Laan, S.W (Author), von Berg, J. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Online Access:View Fulltext in Publisher