VSS: Variance-stabilized signals for sequencing-based genomic signals

Motivation: A sequencing-based genomic assay such as ChIP-seq outputs a real-valued signal for each position in the genome that measures the strength of activity at that position. Most genomic signals lack the property of variance stabilization. That is, a difference between 0 and 100 reads usually...

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Bibliographic Details
Main Authors: Bayat, F. (Author), Libbrecht, M. (Author)
Format: Article
Language:English
Published: Oxford University Press 2021
Online Access:View Fulltext in Publisher