VSS: Variance-stabilized signals for sequencing-based genomic signals
Motivation: A sequencing-based genomic assay such as ChIP-seq outputs a real-valued signal for each position in the genome that measures the strength of activity at that position. Most genomic signals lack the property of variance stabilization. That is, a difference between 0 and 100 reads usually...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2021
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Online Access: | View Fulltext in Publisher |