methylGSA: a Bioconductor package and Shiny app for DNA methylation data length bias adjustment in gene set testing

Motivation: An important downstream analysis following differential expression from RNA sequencing (RNA-Seq) or DNA methylation analysis is the gene set testing to relate significant genes or CpGs to known biological properties. However, the traditional gene set testing approaches result in biased P...

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Bibliographic Details
Main Authors: Kuan, P.F (Author), Ren, X. (Author)
Format: Article
Language:English
Published: Oxford University Press 2018
Subjects:
Online Access:View Fulltext in Publisher