Characterization of regulatory transcriptional mechanisms in hepatocyte lipotoxicity

Non-alcoholic fatty liver disease is a continuum of disorders among which non-alcoholic steatohepatitis (NASH) is particularly associated with a negative prognosis. Hepatocyte lipotoxicity is one of the main pathogenic factors of liver fibrosis and NASH. However, the molecular mechanisms regulating...

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Bibliographic Details
Main Authors: Handschin, C. (Author), Karrer-Cardel, B. (Author), Pérez-Schindler, J. (Author), Ritz, D. (Author), Schmidt, A. (Author), Vargas-Fernández, E. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher