People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells

People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells

CCR5 is the main HIV co-receptor. We aimed to (1) compare CCR5 expression on immune cells between people living with HIV (PLHIV) using combination antiretroviral therapy (cART) and HIV-uninfected controls, (2) relate CCR5 expression to viral reservoir size and (3) assess determinants of CCR5 express...

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Bibliographic Details
Main Authors: Blaauw, M.J.T (Author), de Jonge, M.I (Author), de Mast, Q. (Author), Joosten, L.A.B (Author), Koenen, H.J.P.M (Author), Li, Y. (Author), Matzaraki, V. (Author), Netea, M.G (Author), Trypsteen, W. (Author), van de Wijer, L. (Author), van der Ven, A.J.A.M (Author), van Eekeren, L.E (Author), Vandekerckhove, L. (Author), Zhang, Z. (Author)
Format: Article
Language:English
Published: Nature Research 2022
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