Enrichment of cancer-predisposing germline variants in adult and pediatric patients with acute lymphoblastic leukemia

Despite recent progress in acute lymphoblastic leukemia (ALL) therapies, a significant subset of adult and pediatric ALL patients has a dismal prognosis. Better understanding of leukemogenesis and recognition of germline genetic changes may provide new tools for treating patients. Given that hematop...

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Bibliographic Details
Main Authors: Douglas, S.P.M (Author), Heckman, C.A (Author), Jahnukainen, K. (Author), Keränen, M.A.I (Author), Kilpivaara, O. (Author), Koskenvuo, M. (Author), Koski, J.R (Author), Lahtinen, A.K (Author), Leimi, L. (Author), Pitkänen, E. (Author), Wartiovaara-Kautto, U. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher