Pathogenic nsSNPs that increase the risks of cancers among the Orang Asli and Malays

Pathogenic nsSNPs that increase the risks of cancers among the Orang Asli and Malays

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Single-nucleotide polymorphisms (SNPs) are the most common genetic variations for various complex human diseases, including cancers. Genome-wide association studies (GWAS) have identified numerous SNPs that increase cancer risks, such as breast cancer, colorectal cancer, and leukemia. These SNPs wer...

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Bibliographic Details
Main Authors: Khoruddin, N.A (Author), Mohd Yusof, F.Z (Author), Noorizhab, M.N.F (Author), Salleh, M.Z (Author), Teh, L.K (Author)
Format: Article
Language:English
Published: Nature Research 2021
Series:Scientific Reports
Subjects:
biology
chemistry
Computational Biology
computer simulation
Computer Simulation
conserved sequence
Conserved Sequence
Databases, Genetic
ethnic group
Ethnic Groups
FARP2 protein, human
female
Female
genetic database
genetic predisposition
Genetic Predisposition to Disease
genetics
genome-wide association study
Genome-Wide Association Study
guanine nucleotide exchange factor
Guanine Nucleotide Exchange Factors
human
Humans
Malaysia
male
Male
Models, Molecular
molecular docking
Molecular Docking Simulation
molecular model
monophenol monooxygenase
Monophenol Monooxygenase
mutant protein
Mutant Proteins
mutation
Mutation
neoplasm
Neoplasms
Polymorphism, Single Nucleotide
protein domain
Protein Interaction Domains and Motifs
protein stability
Protein Stability
single nucleotide polymorphism
structural homology
Structural Homology, Protein
whole exome sequencing
Whole Exome Sequencing
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