The in vitro micronucleus assay using imaging flow cytometry and deep learning

The in vitro micronucleus (MN) assay is a well-established assay for quantification of DNA damage, and is required by regulatory bodies worldwide to screen chemicals for genetic toxicity. The MN assay is performed in two variations: scoring MN in cytokinesis-blocked binucleated cells or directly in...

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Bibliographic Details
Main Authors: Davidson, B. (Author), Li, Y. (Author), Probst, C.E (Author), Riedel, M. (Author), Rodrigues, M.A (Author), Venkatachalam, V. (Author), Zayats, A. (Author)
Format: Article
Language:English
Published: Nature Research 2021
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Online Access:View Fulltext in Publisher

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