The in vitro micronucleus assay using imaging flow cytometry and deep learning
The in vitro micronucleus (MN) assay is a well-established assay for quantification of DNA damage, and is required by regulatory bodies worldwide to screen chemicals for genetic toxicity. The MN assay is performed in two variations: scoring MN in cytokinesis-blocked binucleated cells or directly in...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Research
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |