Integrative computational approach identifies drug targets in CD4+ T-cell-mediated immune disorders
CD4+ T cells provide adaptive immunity against pathogens and abnormal cells, and they are also associated with various immune-related diseases. CD4+ T cells’ metabolism is dysregulated in these pathologies and represents an opportunity for drug discovery and development. Genome-scale metabolic model...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Research
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |