Three-dimensional structure determination of protein complexes using matrix-landing mass spectrometry

Native mass spectrometry (MS) is increasingly used to provide complementary data to electron microscopy (EM) for protein structure characterization. Beyond the ability to provide mass measurements of gas-phase biomolecular ions, MS instruments offer the ability to purify, select, and precisely contr...

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Bibliographic Details
Main Authors: Coon, J.J (Author), Grant, T. (Author), Lee, K.W (Author), Lodge, J.M (Author), Salome, A.Z (Author), Westphall, M.S (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher