Knockdown of GABAA alpha3 subunits on thalamic reticular neurons enhances deep sleep in mice
Identification of mechanisms which increase deep sleep could lead to novel treatments which promote the restorative effects of sleep. Here, we show that knockdown of the α3 GABAA-receptor subunit from parvalbumin neurons in the thalamic reticular nucleus using CRISPR-Cas9 gene editing increased the...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
NLM (Medline)
2022
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| Online Access: | View Fulltext in Publisher |