CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling

Chromodomain helicase DNA-binding protein 7 (CHD7), an ATP-dependent eukaryotic chromatin remodeling enzyme, is essential for the development of organs. The mutation of CHD7 is the main cause of CHARGE syndrome, but its function and mechanism in skeletal system remain unclear. Here, we show conditio...

Full description

Bibliographic Details
Main Authors: Duan, X. (Author), Gong, P. (Author), Jiang, S. (Author), Kang, N. (Author), Li, Q. (Author), Lin, W. (Author), Liu, C. (Author), Wang, Y. (Author), Xiong, Q. (Author), Zhang, D. (Author)
Format: Article
Language:English
Published: Nature Research 2022
Online Access:View Fulltext in Publisher