DNA sequence-dependent formation of heterochromatin nanodomains

The mammalian epigenome contains thousands of heterochromatin nanodomains (HNDs) marked by di- and trimethylation of histone H3 at lysine 9 (H3K9me2/3), which have a typical size of 3–10 nucleosomes. However, what governs HND location and extension is only partly understood. Here, we address this is...

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Bibliographic Details
Main Authors: Clarkson, C.T (Author), Mamayusupova, H. (Author), Rademacher, A. (Author), Rippe, K. (Author), Schotta, G. (Author), Teif, V.B (Author), Thorn, G.J (Author)
Format: Article
Language:English
Published: Nature Research 2022
Subjects:
DNA
Online Access:View Fulltext in Publisher