Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance

Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance

Inflammatory conditions are frequently accompanied by increased levels of active proteases, and there is rising interest in methods for their detection to monitor inflammation in a point of care setting. In this work, new sensor materials for disposable single-step protease biosensors based on poly(...

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Bibliographic Details
Main Authors: Ahmad, N. (Author), Becer, C.R (Author), Colak, B. (Author), Gautrot, J.E (Author), Gibbs, M.J (Author), Krause, S. (Author), Watkinson, M. (Author), Zhang, D.-W (Author)
Format: Article
Language:English
Published: American Chemical Society 2019
Subjects:
Article
Biosensing Techniques
chemistry
click chemistry
concentration (parameter)
Concentration ranges
Cross-link densities
Crosslinking
degradation
Degradation
enzyme analysis
gelatinase B
genetic procedures
gold
Gold coatings
human
Humans
hydrogel
Hydrogels
Inflammatory conditions
limit of detection
Lower limit of detections
Matrix Metalloproteinase 9
Matrix metalloproteinase 9 (MMP 9)
MMP9 protein, human
Multiple sclerosis
oxazole derivative
Oxazoles
oxazoline derivative
Pathology
peptide
Peptides
poly(2 oxazoline)
poly(2-oxazoline)
priority journal
protein cross linking
proteinase
Quartz
quartz crystal microbalance
Quartz Crystal Microbalance Techniques
Quartz crystal microbalances
Strong dependences
thiol
Thiol-ene click chemistries
unclassified drug
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