Sonopermeation Enhances Uptake and Therapeutic Effect of Free and Encapsulated Cabazitaxel

Sonopermeation Enhances Uptake and Therapeutic Effect of Free and Encapsulated Cabazitaxel

Delivery of drugs and nanomedicines to tumors is often heterogeneous and insufficient and, thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to improve delivery to tumors, enhancing accumulation and penetration. We used a subcutaneous prostate cancer xenograft mo...

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Bibliographic Details
Main Authors: Åslund, A. (Author), Berg, S. (Author), Davies, C.D.L (Author), Hansen, R. (Author), Mørch, Ý (Author), Pedersen, A. (Author), Snipstad, S. (Author), Sulheim, E. (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2021
Subjects:
animal
animal cell
animal tissue
Animals
Article
Bagg albino mouse
bioaccumulation
body weight
cabazitaxel
Cabazitaxel
cancer survival
cancer tissue
Cavitation
cell culture
circulation time
Combined Modality Therapy
Controlled drug delivery
controlled study
Diseases
Drug delivery
drug delivery system
Drug Delivery Systems
drug efficacy
drug formulation
drug uptake
Enhanced uptake
female
Heterografts
image analysis
male
Male
Mammals
Mice
Mice, Inbred BALB C
microbubble
Microbubbles
mouse
multimodality cancer therapy
nanoencapsulation
Nanoformulation
Nanomedicine
nanoparticle
Nanoparticles
nonhuman
prediction
priority journal
procedures
prostate cancer
Prostate cancers
prostate tumor
Prostatic Neoplasms
Sonochemotherapy
Sonopermeation
Sonoporation
Targeted drug delivery
taxoid
Taxoids
Therapeutic effects
treatment duration
Treatment group
treatment outcome
Treatment Outcome
treatment response
Tumor biology
tumor growth
Tumor growth
tumor xenograft
Tumors
Ultrasonic Therapy
Ultrasonics
Ultrasound
ultrasound targeted microbubble destruction
ultrasound therapy
Ultrasound treatments
xenograft
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