Generation and characterization of a genetic Parkinson's disease-patient derived iPSC line DJ-1-delP (LCSBi008-A)

Here, we describe an induced pluripotent stem cell (iPSC) line that was derived from fibroblasts obtained from a monogenic Parkinson's disease (PD) patient. The disease was caused by a c.634-636delGCC mutation in the PARK7 gene leading to p.158P deletion in the protein DJ-1. iPSCs were generate...

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Bibliographic Details
Main Authors: Bonifati, V. (Author), Boon, A.J.W (Author), Boussaad, I. (Author), Kievit, A.J.A (Author), Krüger, R. (Author), Mandemakers, W. (Author), Mencke, P. (Author), Önal, G. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2022
Online Access:View Fulltext in Publisher