Correlation of hypoxia PET tracer uptake with hypoxic radioresistance in cancer cells: PET biomarkers of resistance to stereotactic radiation therapy?

Purpose: The pO2 threshold of an ideal PET hypoxia tracer for radiotherapy planning in cancer would match those observed in clinically and biologically relevant processes such as radioresistance and HIF1α expression. To identify such tracers, we directly compared uptake in vitro of hypoxia PET trace...

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Bibliographic Details
Main Authors: Blower, P.J (Author), Chia, K. (Author), Landau, D. (Author), Mullen, G.E.D (Author), Naeem, M. (Author), Paul, R.L (Author), Weeks, A.J (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2022
Subjects:
PET
Online Access:View Fulltext in Publisher