Leveraging the preformed fibril model to distinguish between alpha-synuclein inclusion- and nigrostriatal degeneration-associated immunogenicity

Neuroinflammation has become a well-accepted pathologic hallmark of Parkinson's disease (PD). However, it remains unclear whether inflammation, triggered by α-syn aggregation and/or degeneration, contributes to the progression of the disease. Studies examining neuroinflammation in PD are unable...

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Bibliographic Details
Main Authors: Sortwell, C.E (Author), Stoll, A.C (Author)
Format: Article
Language:English
Published: Academic Press Inc. 2022
Subjects:
Online Access:View Fulltext in Publisher