Insulin-like growth factor 2 promotes osteoclastogenesis increasing inflammatory cytokine levels under hypoxia
Osteoporosis is caused by an imbalance in bone remodeling due to abnormal osteoclast (OC) formation and activation. Hypoxia at the site of inflammation promotes OC formation and activation in various species, including humans. We previously reported that insulin-like growth factor 2 (IGF2) plays an...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Japanese Pharmacological Society
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |