Biological Analysis of Simvastatin-releasing Chitosan Scaffold as a Cell-free System for Pulp-dentin Regeneration

Biological Analysis of Simvastatin-releasing Chitosan Scaffold as a Cell-free System for Pulp-dentin Regeneration

Introduction: The improvement of biomaterials capable of driving the regeneration of the pulp-dentin complex mediated by resident cells is the goal of regenerative dentistry. In the present investigation, a chitosan scaffold (CHSC) that released bioactive concentrations of simvastatin (SIM) was test...

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Bibliographic Details
Main Authors: Anovazzi, G. (Author), Basso, F.G (Author), Bordini, E.A.F (Author), de Souza Costa, C.A (Author), Hebling, J. (Author), Silva Leite, M.L.A (Author), Soares, D.G (Author), Zuta, U.O (Author)
Format: Article
Language:English
Published: Elsevier Inc. 2018
Subjects:
cell culture
Cell differentiation
cell free system
Cell-Free System
Cells, Cultured
chitosan
Chitosan
dental pulp
Dental Pulp
dentin
Dentin
dose response
Dose-Response Relationship, Drug
drug effect
human
Humans
male
Male
physiology
procedures
regeneration
Regeneration
Regenerative Endodontics
scaffolds
simvastatin
Simvastatin
tissue engineering
Tissue Engineering
tissue scaffold
Tissue Scaffolds
tooth pulp
young adult
Young Adult
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