The safety and tolerability of aripiprazole once-monthly as maintenance treatment for bipolar I disorder: A double-blind, placebo-controlled, randomized withdrawal study

The safety and tolerability of aripiprazole once-monthly as maintenance treatment for bipolar I disorder: A double-blind, placebo-controlled, randomized withdrawal study

Background: Aripiprazole once-monthly 400 mg (AOM 400), an atypical long-acting injectable antipsychotic, has demonstrated efficacy and safety in maintenance treatment of bipolar I disorder (BP-I). We further assess safety and tolerability and characterize adverse events (AEs) across the duration of...

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Bibliographic Details
Main Authors: Amatniek, J. (Author), Calabrese, J.R (Author), Carson, W.H (Author), Cox, K. (Author), Hertel, P. (Author), Jin, N. (Author), Johnson, B. (Author), McQuade, R.D (Author), Nyilas, M. (Author), Perry, P.P (Author), Sanchez, R. (Author), Such, P. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2018
Subjects:
Administration, Oral
adolescent
Adolescent
adult
Adult
aged
Aged
akathisia
Antipsychotic Agents
aripiprazole
Aripiprazole
Aripiprazole once-monthly
Article
bipolar disorder
Bipolar Disorder
bipolar I disorder
Bipolar I disorder
body weight gain
conduct disorder
Conduct Disorder
controlled study
double blind procedure
Double-Blind Method
drug safety
drug stability
drug tolerability
drug withdrawal
dyskinesia
extrapyramidal symptom
female
Female
human
Humans
injection site reaction
Long-acting injectable antipsychotic
maintenance chemotherapy
Maintenance Chemotherapy
maintenance therapy
Maintenance therapy
major clinical study
male
Male
middle aged
Middle Aged
neuroleptic agent
oral drug administration
parkinsonism
pathophysiology
placebo
priority journal
Psychomotor Agitation
randomized controlled trial
restlessness
side effect
Substance Withdrawal Syndrome
suicide
Weight Gain
withdrawal syndrome
young adult
Young Adult
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