Influence of molecular weight fractionation on the antimicrobial and anticancer properties of a fucoidan rich-extract from the macroalgae Fucus vesiculosus

Influence of molecular weight fractionation on the antimicrobial and anticancer properties of a fucoidan rich-extract from the macroalgae Fucus vesiculosus

The objective of this study was to investigate the antimicrobial and anticancer properties of a fucoidan extract and subsequent fractions isolated from the macroalgae Fucus vesiculosus. The fractions obtained (>300 kDa, <300 kDa, <100 kDa, <50 kDa and <10 kDa) could inhibit the growth...

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Bibliographic Details
Main Authors: Cabral, E.M (Author), Curtin, J. (Author), Devereux, M. (Author), Fitzpatrick, S. (Author), Garcia-Vaquero, M. (Author), Mondala, J.R.M (Author), Oliveira, M. (Author), O'Shea, D. (Author), Przyborska, J. (Author), Rai, D.K (Author), Sivagnanam, S.P (Author), Tiwari, B.K (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2021
Subjects:
algal extract
Anticancer properties
antiinfective agent
Anti-Infective Agents
antimicrobial activity
Antimicrobial properties
antineoplastic activity
antineoplastic agent
Antineoplastic Agents
Article
Bacillus subtilis
Bacteria
bacterial growth
bacterial strain
bacterium
Brain Neoplasms
brain tumor
Brown macroalgae
Cell Line, Tumor
cell survival
Cell Survival
cell viability
chemistry
clinical effectiveness
controlled study
cytotoxicity
drug effect
drug efficacy
drug mechanism
drug response
Escherichia coli
Fucoidan
fucoidin
Fucus
Fucus vesiculosus
glioma
Glioma
growth, development and aging
human
human cell
Humans
IC50
Industrial Microbiology
Inhibitory Concentration 50
isolation and purification
Laminarin
Listeria
Listeria innocua
metabolism
microbial sensitivity test
Microbial Sensitivity Tests
microbiology
molecular weight
Molecular Weight
nonhuman
optical density
pathology
polysaccharide
Polysaccharides
Pseudomonas fluorescens
resazurin assay
tumor cell line
U-251MG cell line
Weight fractionation
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