Dissecting biological activities of fibroblast growth factor receptors by the coiled-coil-mediated oligomerization of FGF1

Dissecting biological activities of fibroblast growth factor receptors by the coiled-coil-mediated oligomerization of FGF1

Fibroblast growth factor receptors (FGFRs) are integral membrane proteins involved in various biological processes including proliferation, migration and apoptosis. There are a number of regulatory mechanisms of FGFR signaling, which tightly control the specificity and duration of transmitted signal...

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Bibliographic Details
Main Authors: Czyrek, A. (Author), Jastrzebski, K. (Author), Knapik, A. (Author), Krzyscik, M.A (Author), Kucinska, M. (Author), Opalinski, L. (Author), Otlewski, J. (Author), Porebska, N. (Author), Pozniak, M. (Author), Zakrzewska, M. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2021
Subjects:
3T3-L1 cell line
3T3-L1 Cells
affinity chromatography
animal
animal cell
animal tissue
Animals
apoptosis
Article
binding competition
Binding, Competitive
Cell division
Cell Line, Tumor
cell metabolism
cell migration
cell proliferation
Cell Proliferation
chemistry
controlled study
drug delivery system
embryo
FGFR
fibroblast growth factor 1
Fibroblast Growth Factor 1
fibroblast growth factor receptor
fluorescence microscopy
glucose transport
heparin
Heparin
human
Humans
internalization (cell)
metabolism
Metabolism
Mice
Microscopy, Fluorescence
mouse
NIH 3T3 cell line
NIH 3T3 Cells
nonhuman
oligomerization
Oligomerization
protein analysis
protein binding
Protein Binding
protein function
protein motif
protein multimerization
Protein Multimerization
protein protein interaction
protein stability
Protein transport
Receptors, Fibroblast Growth Factor
regenerative medicine
signal transduction
Signal Transduction
Signaling
size exclusion chromatography
tumor cell line
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