Reasonable permutation of M2e enhances the effect of universal influenza nanovaccine

Reasonable permutation of M2e enhances the effect of universal influenza nanovaccine

Influenza A virus (IAV) occasionally cross-species transmission among humans, swine and avian. The ectodomain of matrix protein 2 (M2e) is highly conserved in IAV, and multi-copy M2e from different species are usually displayed on the surface of nanoparticles to improve immunogenicity and constitute...

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Bibliographic Details
Main Authors: Chen, Y. (Author), Ding, P. (Author), Jia, R. (Author), Li, G. (Author), Liu, H. (Author), Liu, Y. (Author), Wang, A. (Author), Wang, Y. (Author), Zhang, G. (Author)
Format: Article
Language:English
Published: Elsevier B.V. 2021
Subjects:
animal
Animals
bird
Birds
capsid protein
Capsid Proteins
chemistry
Circovirus
female
Female
fusion protein
human
Humans
immunization
Immunization
immunology
Influenza A virus
influenza vaccine
Influenza Vaccines
lymphocyte antigen receptor
M1 protein, Influenza A virus
M2e-based universal nanovaccine
matrix protein
metabolism
Mice
mouse
nanoparticle
Nanoparticles
pig
Porcine circovirus type 2
protein conformation
Protein Conformation
protein domain
Protein Domains
Receptors, Antigen, B-Cell
Recombinant Fusion Proteins
Swine
vaccine
Vaccines, Combined
Viral Matrix Proteins
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