Resting parasympathetic dysfunction predicts prosocial helping deficits in behavioral variant frontotemporal dementia

Resting parasympathetic dysfunction predicts prosocial helping deficits in behavioral variant frontotemporal dementia

In the behavioral variant of frontotemporal dementia (bvFTD), left-lateralized salience network dysfunction reduces basal activity in the parasympathetic nervous system, a branch of the autonomic nervous system that reduces arousal and fosters empathy and prosociality. Here we examined whether resti...

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Bibliographic Details
Main Authors: Datta, S. (Author), Hua, A.Y (Author), Kramer, J.H (Author), Miller, B.L (Author), Perry, D.C (Author), Rosen, H.J (Author), Seeley, W.W (Author), Sible, I.J (Author), Sturm, V.E (Author)
Format: Article
Language:English
Published: Masson SpA 2018
Subjects:
adult
aged
Aged
Alzheimer disease
Alzheimer Disease
Article
autonomic neuropathy
brain
Brain
brain mapping
Brain Mapping
cholinergic system
Compassion
controlled study
cooperation
diagnostic imaging
empathy
Empathy
exploratory factor analysis
female
Female
frontal variant frontotemporal dementia
frontotemporal dementia
Frontotemporal Dementia
Helping Behavior
human
Humans
laboratory test
Magnetic Resonance Imaging
major clinical study
male
Male
middle aged
Middle Aged
Neurodegenerative disease
neuroimaging
neuropsychological test
Neuropsychological Tests
nuclear magnetic resonance imaging
parasympathetic dysfunction
Parasympathetic Nervous System
pathophysiology
physiology
prosocial behavior
psychology
respiratory sinus arrhythmia
salience network
Salience network
skin conductance
social behavior
task performance
Vagus nerve
voxel based morphometry
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