Suppression of COX-2/PGE2 levels by carbazole-linked triazoles via modulating methylglyoxal-AGEs and glucose-AGEs – induced ROS/NF-κB signaling in monocytes
Chronic hyperglycemia favours the formation of advanced glycation end products (AGEs) which are responsible of many diabetic vascular complications. Keeping in view the medicinal properties of the1,2,3-triazole-conjugated analogs, the present study was designed to evaluate the possible effect of car...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier Inc.
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |