Comparative transcriptomics analysis of Streptococcus mutans with disruption of LuxS/AI-2 quorum sensing and recovery of methyl cycle

Comparative transcriptomics analysis of Streptococcus mutans with disruption of LuxS/AI-2 quorum sensing and recovery of methyl cycle

Objective: The LuxS/AI-2 quorum sensing (QS) system has critical roles in Streptococcus mutans cariogenicity. Whereas the molecular and cellular mechanisms of the LuxS/AI-2 QS system are not thoroughly understood. Given that LuxS has roles in QS and methyl cycle, its mutation can cause QS deficiency...

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Bibliographic Details
Main Authors: Hou, L. (Author), Huang, Z. (Author), Jin, Q. (Author), Mao, M. (Author), Niu, C. (Author), Wang, R. (Author), Yuan, K. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2021
Subjects:
AI-2
bacterial protein
Bacterial Proteins
Carbon-Sulfur Lyases
gene expression regulation
Gene Expression Regulation, Bacterial
genetics
homoserine
Homoserine
lactone
Lactones
LuxS
lyase
metabolism
Methyl cycle
quorum sensing
Quorum sensing
Quorum Sensing
Streptococcus mutans
transcriptome
Transcriptome
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