Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension: The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study

Background: Cardiovascular disease is the leading cause of death throughout the world, with the majority of deaths occurring in low- and middle-income countries. Despite clear evidence for the benefits of blood pressure reduction and availability of safe and low-cost medications, most individuals ar...

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Bibliographic Details
Main Authors:	Camacho, P.A (Author), Islam, S. (Author), Lamelas, P. (Author), Lopez-Jaramillo, P. (Author), Lopez-Lopez, J. (Author), Majid, F. (Author), McCready, T. (Author), McKee, M. (Author), Musa, H. (Author), Schwalm, J.-D.R (Author), Thabane, L. (Author), Yusoff, K. (Author), Yusuf, S. (Author)
Format:	Article
Language:	English
Published:	Mosby Inc. 2018
Subjects:	adult algorithm amlodipine antihypertensive agent Antihypertensive Agents antihypertensive therapy Article blood pressure Blood Pressure candesartan cardiovascular disease cardiovascular risk cause of death Cause of Death clinical evaluation clinical supervision clinical trial cluster analysis Colombia community community care controlled study cost control diabetes mellitus disease management Disease Management drug megadose economic evaluation epidemiology evidence based medicine female Female follow up Follow-Up Studies Framingham risk score health care personnel health care system human Humans hydrochlorothiazide hypercholesterolemia hyperlipidemia hypertension Hypertension hypocholesterolemic agent indapamide Interheart Risk Score intervention study lipid lipid blood level long term care low drug dose major clinical study Malaysia male Male medication compliance middle aged Middle Aged mortality multicenter study outcome assessment Outcome Assessment (Health Care) pathophysiology patient compliance patient counseling perindopril physician physiology priority journal randomized controlled trial risk assessment risk reduction Risk Reduction Behavior scoring system telmisartan time factor Time Factors treatment duration trends valsartan
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Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension: The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study

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