An SNP reducing SNORD105 and PPAN expression decreases the risk of hepatocellular carcinoma in a Chinese population

An SNP reducing SNORD105 and PPAN expression decreases the risk of hepatocellular carcinoma in a Chinese population

Background: With hepatocellular carcinoma (HCC) becoming a heavy disease burden in China, it is particular to reveal its pathological mechanism. Recent researches have indicated that small nucleolar RNAs (snoRNAs) may be involved in various cancers including HCC. Polymorphisms within snoRNAs may aff...

Full description

Bibliographic Details
Main Authors: Chen, X. (Author), Gao, Y. (Author), He, Y. (Author), Li, L. (Author), Qu, Y. (Author), Tan, R. (Author), Yang, Z. (Author), Yu, H. (Author), Zhang, Q. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
Article
Asian
Asians
cancer risk
cancer susceptibility
Carcinoma, Hepatocellular
case control study
Case-Control Studies
cell motility
cell motion
Cell Movement
cell viability
Chinese
controlled study
correlation analysis
female
Female
gene expression
gene expression regulation
Gene Expression Regulation, Neoplastic
gene overexpression
genetic association
Genetic Association Studies
genetic association study
genetic predisposition
Genetic Predisposition to Disease
genetics
genotype phenotype correlation
hepatocellular carcinoma
Hep-G2 cell line
Huh-7 cell line
human
Humans
in vivo study
liver cell carcinoma
Liver Neoplasms
liver tumor
major clinical study
male
Male
middle aged
Middle Aged
nuclear protein
Nuclear Proteins
pathology
Peter Pan protein
Polymorphism, Single Nucleotide
PPAN
PPAN protein, human
protein expression
real time polymerase chain reaction
regulator protein
risk reduction
RNA
RNA extraction
RNA, Small Nucleolar
rs2305789
single nucleotide polymorphism
small nucleolar RNA
SNORD105
SNORD105B RNA, human
unclassified drug
upregulation
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items