The lower expression of circulating miR-210 and elevated serum levels of HIF-1α in ischemic stroke; Possible markers for diagnosis and disease prediction

The lower expression of circulating miR-210 and elevated serum levels of HIF-1α in ischemic stroke; Possible markers for diagnosis and disease prediction

Background: Stroke, either due to ischemia or hemorrhage, causes acute neurological damages to the brain. There is shortage of reliable biomarkers for ischemic stroke (IS), and we therefore investigated the serum concentrations of microRNA-210 (miR-210) and hypoxia inducible factor-1α (HIF-1α), as p...

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Bibliographic Details
Main Authors: Ferns, G.A (Author), Mobarra, N. (Author), Rahmati, M. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
aged
Aged
Area Under Curve
area under the curve
Article
biological marker
biomarker
Biomarkers
blood
brain ischemia
cell free nucleic acid
Cell-Free Nucleic Acids
controlled study
diagnosis
diagnostic accuracy
diagnostic test accuracy study
genetics
HIF1A protein, human
HIF-1α
human
Humans
hypoxia inducible factor 1alpha
Hypoxia-Inducible Factor 1, alpha Subunit
ischemic stroke
Ischemic stroke
Ischemic Stroke
major clinical study
microRNA
microRNA 210
microRNA-210
MicroRNAs
MIRN210 microRNA, human
mortality
prediction
prognosis
Prognosis
protein blood level
sensitivity and specificity
Sensitivity and Specificity
survival analysis
Survival Analysis
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