Association of DYNC1H1 gene SNP/CNV with disease susceptibility, GCs efficacy, HRQOL, anxiety, and depression in Chinese SLE patients

Association of DYNC1H1 gene SNP/CNV with disease susceptibility, GCs efficacy, HRQOL, anxiety, and depression in Chinese SLE patients

Background: Systemic lupus erythematosus is a heterogeneous autoimmune disease characterized by multi-system injuries and overproduction of autoantibodies. There are many genetic studies on SLE, but no report has considered the relationship between cytoplasmic dynein and SLE susceptibility. Objectiv...

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Bibliographic Details
Main Authors: Cai, J. (Author), Chen, Y. (Author), Huang, H. (Author), Huang, S. (Author), Li, M. (Author), Li, Z. (Author), Liu, S. (Author), Lou, Q. (Author), Teng, Y. (Author), Wang, L. (Author), Wang, Y. (Author), Xu, Z. (Author), Yan, Z. (Author), Zhang, T. (Author), Zou, Y. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
allele
anxiety
Anxiety
anxiety disorder
Article
Asian
Asians
case control study
Case-Control Studies
China
controlled study
copy number variation
cytoplasmic dynein
Cytoplasmic Dyneins
depression
Depression
disease predisposition
DNA Copy Number Variations
drug efficacy
DYNC1H1 gene
DYNC1H1 protein, human
female
Female
follow up
gene
gene frequency
Gene Frequency
genetic association
genetic model
genetic predisposition
Genetic Predisposition to Disease
genetics
glucocorticoid
glucocorticoids
Glucocorticoids
Hamilton Anxiety Scale
Hamilton Depression Rating Scale
haplotype
Haplotypes
human
Humans
Lupus Erythematosus, Systemic
major clinical study
male
Male
pain
photosensitization
Polymorphism, Single Nucleotide
prednisone
psychology
quality of life
Quality of Life
sex difference
single nucleotide polymorphism
systemic lupus erythematosus
treatment outcome
Treatment Outcome
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