Associations of PER3 polymorphisms with clopidogrel resistance among Chinese Han people treated with clopidogrel

Associations of PER3 polymorphisms with clopidogrel resistance among Chinese Han people treated with clopidogrel

Background: Changes in circadian rhythm are related to various diseases, such as immune system diseases and cardiovascular diseases. The PERIOD3 (PER3) clock gene is one of the most important genes in the rhythm regulation system. Our goal was to evaluate the possible association between the PER3 rs...

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Bibliographic Details
Main Authors:	Chen, X. (Author), Su, J. (Author), Xu, Z. (Author), Yang, J. (Author), Yin, F. (Author), Yu, Q. (Author), Zheng, N. (Author), Zhong, J. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	acetylsalicylic acid acute coronary syndrome adult aged Aged albumin albumin blood level Article Asian continental ancestry group Asian Continental Ancestry Group Blood Platelets case control study Case-Control Studies circadian rhythm signaling protein clopidogrel Clopidogrel clopidogrel resistance controlled study drug effect drug resistance Drug Resistance ethnic group Ethnic Groups female Female gene gene frequency genetic association Genetic Association Studies genetic association study genetic risk genetics genotype groups by age Han Chinese high risk patient human human cell Humans loading drug dose Logistic Models major clinical study male Male metabolism middle aged Middle Aged multivariate analysis Multivariate Analysis PER3 gene PER3 protein, human percutaneous coronary interventions Period Circadian Proteins PERIOD3 platelet count plateletcrit Polymorphism, Single Nucleotide single nucleotide polymorphism single-nucleotide polymorphisms statistical model therapy resistance thrombocyte
Online Access:	View Fulltext in Publisher

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