Novel long noncoding RNA LINC02323 promotes cell growth and migration of ovarian cancer via TGF-β receptor 1 by miR-1343-3p

Novel long noncoding RNA LINC02323 promotes cell growth and migration of ovarian cancer via TGF-β receptor 1 by miR-1343-3p

Background: This study was aimed at investigating the effects of long noncoding RNA (lncRNA) LINC02323 in ovarian cancer and its possible mechanism. Methods: Microarray analysis and QPCR were utilized to identify lncRNA LINC02323 expression in patients with ovarian cancer. MTT assay was used for ana...

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Bibliographic Details
Main Authors: Li, Y. (Author), Sun, D. (Author), Zhao, Z. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
Article
blood
cancer patient
carcinogenesis
cell growth
Cell Line, Tumor
cell migration
cell motion
Cell Movement
cell proliferation
Cell Proliferation
controlled study
down regulation
enzyme activity
female
Female
gene expression
gene expression regulation
Gene Expression Regulation, Neoplastic
gene overexpression
gene repression
genetics
human
human cell
Humans
in vitro study
lactate dehydrogenase
LINC02323
LINC02323 gene
L-Lactate Dehydrogenase
long untranslated RNA
metabolism
microarray analysis
microRNA
MicroRNAs
miR 1343 3p gene
miR-1343-3p
MIRN-1343 microRNA, human
mortality
MTT assay
oncogene
ovarian cancer
ovarian cancer cell line
Ovarian Neoplasms
ovary cancer
ovary tumor
pathology
polymerase chain reaction
quantitative analysis
Receptor, Transforming Growth Factor-beta Type I
RNA, Long Noncoding
TGF-β
transforming growth factor beta
Transforming Growth Factor beta
transforming growth factor beta receptor 1
tumor cell line
tumor promotion
upregulation
Western blotting
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