Polygenic risk score for bipolar disorder associates with divergent thinking and brain structures in the prefrontal cortex

It has been hypothesized that a higher genetic risk of bipolar disorder (BD) is associated with greater creativity. Given the clinical importance of bipolar disorder and the importance of creativity to human society and cultural development, it is essential to reveal their associations and the neura...

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Main Authors:	Araki, T. (Author), dos S. Kawata, K.H (Author), Hanawa, S. (Author), Iizuka, K. (Author), Ikeda, S. (Author), Imanishi, T. (Author), Kawashima, R. (Author), Kikuchi, Y. (Author), Kimura, R. (Author), Kotozaki, Y. (Author), Magistro, D. (Author), Matsudaira, I. (Author), Miyauchi, C.M (Author), Nakagawa, S. (Author), Nouchi, R. (Author), Nozawa, T. (Author), Ono, C. (Author), Sakaki, K. (Author), Sekiguchi, A. (Author), Takeuchi, H. (Author), Taki, Y. (Author), Tomita, H. (Author), Yokota, S. (Author), Yokoyama, R. (Author), Yu, Z. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adolescent Adolescent adult Adult anatomy and histology Article bipolar disorder Bipolar Disorder brain region creativity Creativity diagnostic imaging female Female genetic association genetic predisposition Genetic Predisposition to Disease genetic risk genetic risk score genetics genotyping gray matter volume human human experiment Humans inferior frontal gyrus Magnetic Resonance Imaging male Male middle frontal gyrus mood disorder multifactorial inheritance Multifactorial Inheritance neuroimaging nuclear magnetic resonance imaging polygenic risk score prefrontal cortex Prefrontal Cortex risk Risk voxel based morphometry voxel-based morphometry white matter young adult Young Adult
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Polygenic risk score for bipolar disorder associates with divergent thinking and brain structures in the prefrontal cortex

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