VLP-factory™ and ADDomer©: Self-assembling Virus-Like Particle (VLP) Technologies for Multiple Protein and Peptide Epitope Display

VLP-factory™ and ADDomer©: Self-assembling Virus-Like Particle (VLP) Technologies for Multiple Protein and Peptide Epitope Display

Virus-like particles (VLPs) play a prominent role in vaccination as safe and highly versatile alternatives to attenuated or inactivated viruses or subunit vaccines. We present here two innovations, VLP-factory™ and ADDomer©, for creating VLPs displaying entire proteins or peptide epitopes as antigen...

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Bibliographic Details
Main Authors: Berger, I. (Author), Bufton, J. (Author), Fitzgerald, D. (Author), Garzoni, F. (Author), Gupta, K. (Author), Sari-Ak, D. (Author), Schaffitzel, C. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2021
Subjects:
Adenoviridae
animal cell
antigenic epitope
Article
baculovirus expression system
baculovirus expression vector system (BEVS)
capsid protein
controlled study
epitope
Epitopes
genetics
hemagglutinin
Hemagglutinins
human
immunization
influenza vaccine
Influenza Vaccines
Influenza virus
Influenza virus hemagglutinin
insect cell
M1 capsid protein
MultiBac
nonhuman
Orthomyxoviridae
peptide
Peptides
priority journal
protein and peptide display
protein assembly
unclassified drug
vaccination
vaccine
virus envelope
virus particle
virus virulence
virus-like particle (VLP)
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